Accelerating
Drug Discovery Together

Structural Biology CRO & Crystallography

GIOS Biostructures is a structural biology CRO that offers a fully integrated service for structure determination, fragment based screening, de novo protein design and protein engineering. Using our automated X-ray crystallography platform, we can accelerate your research towards novel therapeutics, biomarkers and innovative drug discovery solutions.

Service packages

Gene to protein

Gene to protein

Starting from a gene or protein sequence, we cover cloning, expression and purification, resulting in a highly pure protein product.

Protein to structure

Protein to structure

We deliver high-quality X-ray data and structures through our automated X-ray crystallography platform and synchrotron access.

Fragment-based screening

Fragment-based screening

We offer small-scale X-ray based fragment screening to assess protein druggability and discover druggable sites, including cryptic pockets.

AI-based protein design

AI-based protein design
Our expertise in AI-powered protein design and GIOS MESO platform™ enables de novo protein design and engineering.

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Complete pipeline of services

Our company offers a complete pipeline of services necessary to determine protein structures — from concept to final model. The process begins with a target protein or an idealized scaffold, which can be engineered using AI-driven methods and converted into a corresponding nucleotide sequence. This gene is then introduced into a suitable cellular system for protein expression. Our Protein-to-Structure workflow enables the production of milligram-scale quantities of protein, optimized for crystallization using our high-throughput platform. Finally, the resulting structures are delivered to the customer.

GIOS Biostructures pipeline

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